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Signaling Pathways

Signaling Pathways

A8706 BLU9931

Target: FGFR

Summary: FGFR4 inhibitor,potent and irreversible

≥50.9 mg/mL
A2583 Lactacystin (Synthetic)
1 Citation

Target: Proteasome

Summary: Proteasome inhibitor

Soluble in H2O
A2606 Epoxomicin
25 Citation

Summary: Proteasome inhibitor

≥27.73 mg/mL
A4010 Salinosporamide A (NPI-0052, Marizomib)

Target: Proteasome

Summary: 20S proteasome inhibitor

Soluble in DMSO
A8202 Abiraterone acetate

Target: Cytochrome P450 (CYP450)

Summary: Cytochrome p450 17a1 inhibitor

insoluble in H2O; ≥11.22 mg/mL
A1901 Q-VD-OPh
53 Citation

Target: Caspases

Summary: Cell-permeable, irreversible pan-caspase inhibitor

≥25.67 mg/mL
A4300 GW9662
1 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL
A1921 Z-DQMD-FMK
3 Citation

Target: Caspases

Summary: Caspase-3 inhibitor,cell-permeable

≥29.2 mg/mL
A1933 Carfilzomib (PR-171)
10 Citation

Target: Proteasome

Summary: Proteasome inhibitor, epoxomicin analog

≥35.99 mg/mL
A3420 FMK

Target: Ribosomal s6 kinases (RSK)

Summary: RSK inhibitor

insoluble in H2O; ≥17.1 mg/mL