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Signaling Pathways

Signaling Pathways

A3962 AZD1208

Target: Pim

Summary: PIM kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
A8232 Nilotinib(AMN-107)
1 Citation

Target: Bcr-Abl

Summary: Bcr-Abl kinase inhibitor,selective

≥26.5 mg/mL
A1980 SNS-032 (BMS-387032)
2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK inhibitor

insoluble in H2O; ≥19.05 mg/mL
A5793 Quizartinib (AC220)

Target: FLT3

Summary: FLT3 inhibitor,potent and selective

≥28.03 mg/mL
A5801 BIX 02189

Target: MEK|ERK

Summary: Selective MEK5 inhibitor

≥22.05 mg/mL
A8316 PD 0332991 (Palbociclib) HCl
5 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥14.48 mg/mL
A8537 Thioridazine HCl

Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors

Summary: Calcium channel protein inhibitor
B1963 Lomustine
1 Citation

Target: RNA synthesis

Summary: Antineoplastic drug

insoluble in H2O; ≥23.41 mg/mL
B4894 SP2509

Target: Histone Demethylases

Summary: Demethylase 1 (LSD1) antagonist, novel Lysine-specific

insoluble in H2O; insoluble in EtOH; ≥19.45 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL