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Signaling Pathways

Signaling Pathways

B1135 GDC-0623

Target: MEK

Summary: MEK1 inhibitor, potent and ATP-uncompetitive

insoluble in H2O; ≥16.85 mg/mL
B1036 MLN4924
5 Citation

Target: NAE|Ubiquitin-activating Enzyme E1|SUMOylation

Summary: NAE inhibitor

≥22.18 mg/mL
B1577 C646
1 Citation

Target: p300

Summary: HAT p300-CBP inhibitor,cell-permeable

insoluble in H2O; ≥11.14 mg/mL
B4896 BMH-21

Target: RNA Polymerases

Summary: RNA polymerase I Inhibitior

insoluble in EtOH; insoluble in H2O; ≥7.4 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
A8177 PAC-1
1 Citation

Target: Caspases

Summary: Procaspase-3 activator

insoluble in H2O; ≥13.4 mg/mL
B3704 Nexturastat A

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor,highly potent and selective

insoluble in H2O; ≥16.3 mg/mL
B3941 Talabostat mesylate
2 Citation

Target: DPP-4

Summary: orally active, specific inhibitor of DPP4

≥11.45 mg/mL
A5790 Cidofovir

Target: CMV

Summary: Anti-CMV drug;inhibitor of viral DNA syntheis

insoluble in EtOH; insoluble in DMSO; ≥13.95 mg/mL
A8316 PD 0332991 (Palbociclib) HCl
5 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥14.48 mg/mL