JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home
Signaling Pathways

Signaling Pathways

A2213 17-DMAG (Alvespimycin) HCl
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

≥26.2 mg/mL
A5793 Quizartinib (AC220)

Target: FLT3

Summary: FLT3 inhibitor,potent and selective

≥28.03 mg/mL
A5801 BIX 02189

Target: MEK|ERK

Summary: Selective MEK5 inhibitor

≥22.05 mg/mL
A8307 Crenolanib (CP-868596)
1 Citation

Target: FLT3|PDGFR

Summary: PDGFR-β inhibitor,potent and selective

≥22.2 mg/mL
A8316 PD 0332991 (Palbociclib) HCl
5 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥14.48 mg/mL
A8335 Palbociclib (PD0332991) Isethionate
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥28.7 mg/mL
A8350 AZD4547

Target: FGFR

Summary: FGFR inhibitor

≥23.2 mg/mL
A8477 MK-8776 (SCH-900776)

Target: Chk

Summary: Chk1 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥18.8 mg/mL
A8537 Thioridazine HCl

Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors

Summary: Calcium channel protein inhibitor
B1963 Lomustine
1 Citation

Target: RNA synthesis

Summary: Antineoplastic drug

insoluble in H2O; ≥23.41 mg/mL