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Signaling Pathways

Signaling Pathways

B2180 AS-252424

Target: Akt|PI3K

Summary: PI3Kγ inhibitor,novel and potent

insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
B1371 Miltefosine

Target: PI3K

Summary: PI3K/Akt inhibitor

≥10.2 mg/mL
B2177 TG100713

Target: PI3K

Summary: pan-PI3K inhibitor

soluble in DMSO
B4492 HS-173

Target: PI3K

Summary: novel PI3K inhibitor

≥21.1 mg/mL
B5831 Acalisib (GS-9820)

Target: PI3K

Summary: PI3Kδ inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8353 3-Methyladenine
3 Citation

Target: PI3K

Summary: Class III PI3K inhibitor

≥5 mg/mL
A8354 A66

Target: PI3K

Summary: P110α inhibitor

insoluble in H2O; ≥19.7 mg/mL
A8488 NVP-BGT226

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor,selective and novel

insoluble in EtOH; insoluble in H2O; ≥16.28 mg/mL