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Signaling Pathways

Signaling Pathways

A8501 PHA-848125

Target: Cyclin-Dependent Kinases

Summary: CDK inhibitor,potent and ATP-competitive

≥23.05 mg/mL
A8385 BMS265246

Target: Cyclin-Dependent Kinases

Summary: CDK1/2 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
A8412 Dinaciclib (SCH727965)
2 Citation

Target: Cyclin-Dependent Kinases

Summary: Potent CDK inhibitor
A8565 Purvalanol B
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK1/CDK2/CDK4 inhibitor

≥21.65 mg/mL
A8616 A-674563

Target: Cyclin-Dependent Kinases|Akt|GSK-3|ERK|PKC|PKA|RSK

Summary: Akt1/PKA/CDK2 inhibitor,potent and selective

insoluble in EtOH; ≥23.8 mg/mL
A8641 LEE011

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
A8642 R547
2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK1/2/4 inhibitor,ATP-competitive

Soluble in DMSO
B3277 AMG 925

Target: Cyclin-Dependent Kinases|FLT3

Summary: FLT3/CDK4 inhibitor,potent and selective

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B4754 LDC000067
2 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK9 inhibitor, novel and highly specific

insoluble in H2O; insoluble in EtOH; ≥18.52 mg/mL
A8885 Ro 3306
4 Citation

Target: Cyclin-Dependent Kinases

Summary: An ATP-competitive, potent CDK1 inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.39 mg/mL