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Signaling Pathways

Signaling Pathways

B4492 HS-173

Target: PI3K

Summary: novel PI3K inhibitor

≥21.1 mg/mL
B5831 Acalisib (GS-9820)

Target: PI3K

Summary: PI3Kδ inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8353 3-Methyladenine
3 Citation

Target: PI3K

Summary: Class III PI3K inhibitor

≥5 mg/mL
A8354 A66

Target: PI3K

Summary: P110α inhibitor

insoluble in H2O; ≥19.7 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL
A8649 NU 7026

Target: PI3K|DNA-PK|ATM

Summary: DNPK inhibitor,ATP-competitive and potent

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B1288 Rigosertib

Target: PI3K|PLK

Summary: PI3K/PLK1 inhibitor

Soluble in DMSO
A8210 GDC-0941
10 Citation

Target: PI3K

Summary: PI3K inhibitor,potent and selective

≥25.7 mg/mL