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Signaling Pathways

Signaling Pathways

A8173 Romidepsin (FK228, depsipeptide)
7 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1/HDAC2 inhibitor, potent and selective

≥27.04 mg/mL
A8176 Apicidin
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
B3704 Nexturastat A

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor,highly potent and selective

insoluble in H2O; ≥16.3 mg/mL
A4083 Rocilinostat (ACY-1215)
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: Selective HDAC6 inhibitor

≥21.675 mg/mL
A4084 Vorinostat (SAHA, MK0683)
9 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4089 Mocetinostat (MGCD0103, MG0103)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,isotype-selective and potent

insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
A4090 JNJ-26481585
3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A4091 PCI-34051
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC8 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL
A4093 ITF2357 (Givinostat)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

≥23.8 mg/mL
A4094 MC1568
3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Class II HDAC inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥15.7 mg/mL