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Signaling Pathways

Signaling Pathways

A3765 Rilpivirine

Target: reverse transcriptase

Summary: Inhibitor of next-generation nonnucleoside reverse transcriptase

insoluble in H2O; ≥12.25 mg/mL
B1533 BMS-378806
1 Citation

Target: gp120/CD4

Summary: Gp120/CD4 inhibitor

insoluble in H2O; insoluble in EtOH; ≥20.2 mg/mL
A8410 Didanosine

Target: Reverse Transcriptases

Summary: Reverse transcriptase inhibitor

insoluble in H2O; insoluble in EtOH; ≥23.61 mg/mL
A8554 Dapivirine (TMC120)

Target: Reverse Transcriptases

Summary: Nonnucleoside reverse transcriptase inhibitor

insoluble in H2O; ≥13.5 mg/mL
A8809 Vorapaxar

Target: Protease-Activated Receptors

Summary: PAR-1 antagonist,potent and orally active

≥24.65 mg/mL