Dapivirine (TMC120)

Catalog No.

A8554

Nonnucleoside reverse transcriptase inhibitor

Grouped product items
Size	Price	Stock
10mM (in 1mL DMSO)	$66.00	In stock
5mg	$61.00	In stock
25mg	$182.00	In stock

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Dapivirine (DPV) is a nonnucleoside reverse transcriptase inhibitor with a favorable safety profile following vaginal application.

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	329.4
Cas No.	244767-67-7
Formula	C₂₀H₁₉N₅
Synonyms	TMC 120;TMC-120
Solubility	insoluble in H2O; ≥13.5 mg/mL in DMSO; ≥5.41 mg/mL in EtOH
Chemical Name	4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile
SDF	Download SDF
Canonical SMILES	Cc(cc1C)cc(C)c1Nc1ccnc(Nc(cc2)ccc2C#N)n1
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Description	Dapivirine (TMC120) is a non-nucleoside inhibitor of HIV reverse transcriptase with an IC50 vaule of 24 nM.
Targets	HIV reverse transcriptase
IC50	24 nM

Purity = 98.00%