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Signaling Pathways

Items 1-10 of 54

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  1. Disulfiram
    A4015 Disulfiram
    Target: Aldehyde Dehydrogenases
    Summary: Dopamine β-hydroxylase inhibitor
      insoluble in H2O; ≥12 mg/mL
  2. AT13387
    A4056 AT13387
    Target: HSP90
    Summary: Hsp90 inhibitor
      insoluble in H2O; ≥13.25 mg/mL
  3. AUY922 (NVP-AUY922)
    A4057 AUY922 (NVP-AUY922)
     1 Citation
    Target: HSP90
    Summary: Potent Hsp90 inhibitor
      ≥23.27 mg/mL
  4. Geldanamycin
    A4060 Geldanamycin
     2 Citation
    Summary: Hsp90 inhibitor,potent and specific
      insoluble in EtOH; insoluble in H2O; ≥16.9 mg/mL
  5. IPI-504 (Retaspimycin hydrochloride)
    A4061 IPI-504 (Retaspimycin hydrochloride)
     3 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor,novel, potent,selective
      ≥26.1 mg/mL
  6. PF-04929113 (SNX-5422)
    A4065 PF-04929113 (SNX-5422)
    Target: HSP90
    Summary: Hsp90 inhibitor,potent and selective
      ≥23.85 mg/mL
  7. SNX-2112
    A4068 SNX-2112
     1 Citation
    Summary: Hsp90 inhibitor,ATP-competitve,potent and selective
      ≥23.05 mg/mL
  8. Abiraterone acetate
    A8202 Abiraterone acetate
    Target: Cytochrome P450 (CYP450)
    Summary: Cytochrome p450 17a1 inhibitor
      insoluble in H2O; ≥11.22 mg/mL
  9. GW9662
    A4300 GW9662
     1 Citation
    Summary: PPARγ antagonist
      insoluble in H2O; ≥13.75 mg/mL
  10. GSK3787
    A4303 GSK3787
    Summary: PPARβ/δ antagonist,novel and irreversible
      insoluble in H2O; ≥15.8 mg/mL

Items 1-10 of 54

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Category
  1. PPAR8item
  2. Carbonic Anhydrase3item
  3. CETP1 item
  4. CYP3A/CYP4502item
  5. Dehydrogenase2item
  6. Dopamine β-hydroxylase3item
  7. FAAH1 item
  8. Factor Xa1 item
  9. HMG-CoA Reductase3item
  10. HSP6item
  11. IDO3item
  12. KRAS-PDEδ1 item
  13. P4503item
  14. PDE9item
  15. Phospholipase2item
  16. Transferase6item
Reversibility
  1. Irreversible5item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases1 item
  2. Factor Xa1 item
  3. Phosphodiesterases (PDEs)7item
  4. RARs1 item
  5. HSP904item
  6. Cytochrome P450 (CYP450)4item
  7. HMG-CoA Reductases3item
  8. DGAT1 item
  9. CETP1 item
  10. Lactate Dehydrogenases (LDH)1 item
  11. Nampt1 item
  12. Carbonic Anhydrases3item
  13. Aldehyde Dehydrogenases2item
  14. Phospholipases1 item
  15. Catechol O-Methyltransferase (COMT)1 item
  16. FPTase1 item
  17. PPAR2item
  18. Ftase1 item
  19. FAAH1 item
  20. IDO1 item
  21. Glycogen Phosphorylases1 item
Related Disease
  1. Acne1 item
  2. Acute Myeloid Leukemia1 item
  3. Bladder Carcinoma1 item
  4. Brain Injuries Studies1 item
  5. Breast Cancer7item
  6. Cancer20item
  7. Cervical Cancer1 item
  8. Chronic Lymphocytic Leukemia1 item
  9. Cocaine-Related Disorders2item
  10. Colon Cancer1 item
  11. Diabetes2item
  12. Dyslipidemia1 item
  13. Erectile Dysfunction2item
  14. Glioblastoma1 item
  15. Glioma1 item
  16. HIV Infections1 item
  17. Inflammation1 item
  18. Inflammatory Diseases1 item
  19. Leukemia1 item
  20. Lung Cancer3item
  21. Lymphoma2item
  22. Melanoma4item
  23. Multiple Myeloma3item
  24. Neuroblastoma3item
  25. Neurocognitive Disorders1 item
  26. Non-small Cell Lung Cancer1 item
  27. Obsessive-Compulsive Disorder1 item
  28. Osteoporosis1 item
  29. Pancreatic Cancer2item
  30. Pancreatic Carcinoma1 item
  31. Prostate Cancer7item
  32. Psoriasis2item
  33. Psoriasis Vulgaris1 item
  34. Rheumatoid Arthritis1 item
  35. Schizophrenia1 item
  36. Type 2 Diabetes1 item