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Signaling Pathways

Signaling Pathways

A4164 AZD2461

Target: PARP

Summary: Novel PARP inhibitor

insoluble in H2O; ≥16.35 mg/mL
A3246 BMN-673 8R,9S
1 Citation

Summary: Inactive form of BMN 673, used as negative control

≥38 mg/mL
A8893 Rucaparib (free base)

Target: PARP

Summary: Potent PARP inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.15 mg/mL
B3393 MK-4827 Racemate

Summary: selective inhibitor of PARP1/PARP2

Soluble in DMSO
A3617 MK-4827

Target: PARP

Summary: PARP-1/-2 inhibitor,potent and selective

≥32 mg/mL
A3729 PJ34

Target: PARP

Summary: PARP-l inhibitor

≥50.9 mg/mL
A3958 Veliparib dihydrochloride

Target: PARP

Summary: PARP-1/PARP-2 inhibitor

≥31.7 mg/mL
A4524 4-HQN

Summary: PARP inhibitor

≥7.4 mg/mL
A4525 BYK 204165

Summary: PARP-1 inhibitor,potent and selective

<25.23 mg/mL
A4526 BYK 49187

Summary: Potent PARP-1/PARP-2 inhibitor

<16.77 mg/mL