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Signaling Pathways

Signaling Pathways

A3002 ABT-888 (Veliparib)
6 Citation

Summary: Potent PARP inhibitor
A4153 BMN 673

Summary: Potent PARP inhibitor
A4154 Olaparib (AZD2281, Ku-0059436)
12 Citation

Summary: Potent PARP1/PARP2 inhibitor

≥21.72 mg/mL
A4156 Rucaparib (AG-014699,PF-01367338)

Summary: Potent PARP inhibitor

≥21.08 mg/mL
A4157 Iniparib (BSI-201)

Summary: PARP1 inhibitor,intravenously adminsitered

insoluble in H2O; ≥103.4 mg/mL
A4158 AG-14361
1 Citation

Summary: Potent PARP1 inhibitor
A4159 PJ34 hydrochloride

Summary: PARP inhibitor,potent and cell-permeable

insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
A4160 A-966492

Target: PARP

Summary: PARP-1/-2 inhibitor, highly potent

≥32.4 mg/mL
A4161 3-aminobenzamide
1 Citation

Summary: Potent PARP inhibitor

≥23.45 mg/mL
A4163 UPF 1069

Target: PARP

Summary: Selective PARP2 inhibitor

insoluble in H2O; ≥12.7 mg/mL