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Signaling Pathways

Signaling Pathways

A4512 Cucurbitacin I

Target: STAT|JAK

Summary: STAT3/JAK2 signaling inhibitor

≥22.45 mg/mL
B8023 Cerdulatinib (PRT062070)

Target: JAK|Syk|TYK2

Summary: Syk/JAK inhibitor

≥22.3 mg/mL
B1130 GLPG0634
1 Citation

Target: JAK

Summary: JAK1 inhibitor

≥21.3 mg/mL
A3012 Ruxolitinib (INCB018424)
4 Citation

Target: JAK

Summary: JAK inhibitor

insoluble in H2O; ≥15.32 mg/mL
A4135 Tofacitinib (CP-690550) Citrate
2 Citation

Target: JAK

Summary: Potent JAK inhibitor

≥25.22 mg/mL
A4136 TG101348 (SAR302503)
2 Citation

Target: FLT3|JAK|c-RET

Summary: JAK-2 inhibitor,potent and selective

≥26.23 mg/mL
A4138 Tofacitinib (CP-690550,Tasocitinib)
1 Citation

Target: JAK

Summary: Janus kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥15.6 mg/mL
A4148 NVP-BSK805 2HCl

Target: JAK

Summary: JAK2 inhibitor

≥30.8 mg/mL
A4151 ZM 39923 HCl

Target: JAK

Summary: JAK3 inhibitor,potent and selective
A4152 BMS-911543

Target: JAK

Summary: JAK2 inhibitor,selective small molecule

≥43.3 mg/mL