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Signaling Pathways

Signaling Pathways

A4166 EPZ5676
1 Citation

Target: DOT1L

Summary: DOT1L inhibitor,potent and SAM competitive

≥28.15 mg/mL
A4168 Entacapone

Target: Catechol O-Methyltransferase (COMT)

Summary: COMT inhibitor
A4171 EPZ005687
2 Citation

Target: EZH2

Summary: EZH2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
A4170 EPZ004777

Target: DOT1L

Summary: DOT1L inhibitor

≥27 mg/mL
A1905 3-Deazaneplanocin,DZNep
6 Citation

Target: Hydrolase

Summary: S-adenosylhomocysteine and EZH2 inhibitor

insoluble in EtOH; ≥17.07 mg/mL
A1909 BIX 01294

Target: G9a

Summary: G9a and GLP inhibitor

≥24.45 mg/mL
B4875 PFI-2
1 Citation

Target: SETD7

Summary: SETD7 methyltransferase inhibitor

≥50 mg/mL
B4989 EPZ015666

Target: Protein Arginine Methyltransferases

Summary: PRMT5 inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.17 mg/mL
B6182 GSK591

Target: PRMT

Summary: PRMT5 inhibitor

≥38 mg/mL
A8182 3-Deazaneplanocin A (DZNep) hydrochloride
1 Citation

Target: EZH2

Summary: SAHH and EZH2 inhibitor

insoluble in EtOH; ≥14.94 mg/mL