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Signaling Pathways

Signaling Pathways

B8210 (R)-PFI 2 hydrochloride

≥26.8 mg/mL
A4166 EPZ5676
1 Citation

Target: DOT1L

Summary: DOT1L inhibitor,potent and SAM competitive

≥28.15 mg/mL
A4168 Entacapone

Target: Catechol O-Methyltransferase (COMT)

Summary: COMT inhibitor
A4171 EPZ005687
2 Citation

Target: EZH2

Summary: EZH2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
A4167 SGC 0946

Summary: DOT1L inhibitor,highly potent and selective

≥30.95 mg/mL
A4170 EPZ004777

Target: DOT1L

Summary: DOT1L inhibitor

≥27 mg/mL
A1905 3-Deazaneplanocin,DZNep
6 Citation

Target: Hydrolase

Summary: S-adenosylhomocysteine and EZH2 inhibitor

insoluble in EtOH; ≥17.07 mg/mL
A1908 AMI-1

Summary: PRMT1 inhibitor

insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL
A1909 BIX 01294

Target: G9a

Summary: G9a and GLP inhibitor

≥24.45 mg/mL
A1914 UNC0638
1 Citation

Summary: G9a/GLP HMTase inhibitor, potent and selective

≥25.5 mg/mL