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Signaling Pathways

Items 1-10 of 11

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  1. Lidocaine
    A1450 Lidocaine
    Target: Histamine H1 Receptors
    Summary: Anasthetic and class Ib antiarrhythmic agent
      insoluble in H2O; ≥11.72 mg/mL
  2. Loratadine
    A2960 Loratadine
    Target: Histamine H1 Receptors
    Summary: Peripheral HH1R antagonist
      insoluble in H2O; ≥19.14 mg/mL
  3. Cetirizine DiHCl
    B1547 Cetirizine DiHCl
    Target: Histamine H1 Receptors
    Summary: H1 receptor inverse agonist
      insoluble in EtOH; ≥2.66 mg/mL
  4. Cyclizine 2HCl
    B1548 Cyclizine 2HCl
    Target: Histamine H1 Receptors
    Summary: Histamine H1 receptor antagonist
      Soluble in DMSO
  5. Hydroxyzine 2HCl
    B1549 Hydroxyzine 2HCl
    Target: Histamine H1 Receptors
    Summary: Histamine H1-receptor antagonist
  6. JNJ-7777120
    B1574 JNJ-7777120
    Target: Histamine H4 Receptors
    Summary: Histamine H4 receptor antagonist
  7. Pemirolast potassium
    B1563 Pemirolast potassium
    Target: Histamine H1 Receptors
    Summary: Histamine H1 receptor antagonist
      insoluble in EtOH; ≥85.4 mg/mL
  8. Ranitidine
    B1564 Ranitidine
    Target: Histamine H2 Receptors
    Summary: Histamine H2-receptor antagonist
      ≥17.54 mg/mL
  9. Azelastine HCl
    B1568 Azelastine HCl
    Target: Histamine H1 Receptors
    Summary: Potent, second-generation, selective, histamine receptor antagonist
      ≥20.92 mg/mL
  10. 4-Methylhistamine dihydrochloride
    B7026 4-Methylhistamine dihydrochloride
    Target: Histamine H4 Receptors
    Summary: H4 receptor agonist
      ≥31.3 mg/mL

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