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Signaling Pathways

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  1. Pitolisant hydrochloride
    A3727 Pitolisant hydrochloride
    Summary: Nonimidazole inverse agonist
      ≥16.6 mg/mL
  2. Cetirizine DiHCl
    B1547 Cetirizine DiHCl
    Target: Histamine H1 Receptors
    Summary: H1 receptor inverse agonist
      insoluble in EtOH; ≥2.66 mg/mL
  3. Cyclizine 2HCl
    B1548 Cyclizine 2HCl
    Target: Histamine H1 Receptors
    Summary: Histamine H1 receptor antagonist
      Soluble in DMSO
  4. Hydroxyzine 2HCl
    B1549 Hydroxyzine 2HCl
    Target: Histamine H1 Receptors
    Summary: Histamine H1-receptor antagonist
  5. JNJ-7777120
    B1574 JNJ-7777120
    Target: Histamine H4 Receptors
    Summary: Histamine H4 receptor antagonist
  6. Pemirolast potassium
    B1563 Pemirolast potassium
    Target: Histamine H1 Receptors
    Summary: Histamine H1 receptor antagonist
      insoluble in EtOH; ≥85.4 mg/mL
  7. Rupatadine Fumarate
    B1566 Rupatadine Fumarate
     1 Citation
    Target: Histamine H1 Receptors|PAFR
    Summary: Inhibitor of PAF and histamine (H1) receptor
      insoluble in H2O; ≥11.75 mg/mL
  8. Ranitidine
    B1564 Ranitidine
    Target: Histamine H2 Receptors
    Summary: Histamine H2-receptor antagonist
      ≥17.54 mg/mL
  9. Azelastine HCl
    B1568 Azelastine HCl
    Target: Histamine H1 Receptors
    Summary: Potent, second-generation, selective, histamine receptor antagonist
      ≥20.92 mg/mL
  10. 2-Pyridylethylamine dihydrochloride
    B7072 2-Pyridylethylamine dihydrochloride
    Target: Histamine H1 Receptors
    Summary: Histamine H1 receptor agonist
      <19.51 mg/mL

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