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Signaling Pathways

Signaling Pathways

A3003 MDV3100 (Enzalutamide)
12 Citation

Target: Androgen Receptors

Summary: Androgen receptor antagonist

≥23.22 mg/mL
A1115 Peptide YY(3-36), PYY, human

Target: NPY Receptors

Summary: Y2R agonist

≥405 mg/mL
A4326 TAK-700 (Orteronel)
2 Citation

Target: human lyase

Summary: Human 17,20-lyase inhibitor

insoluble in H2O; ≥11.2 mg/mL
A1147 Luteinizing hormone releasing hormone human acetate salt (LHRH)

Target: MMP

Summary: acitivator of MMP-2 and MMP-9, selective

≥118.2 mg/mL
A3517 JDTic

Summary: Opioid antagonist

Soluble in DMSO
A3518 JDTic 2HCl

Summary: κ-opioid receptor antagonist

Soluble in DMSO
B5421 (Z)-4-Hydroxytamoxifen

Target: Estrogen and Related Receptors

Summary: ER modulator, potent and selective

≥38.8 mg/mL
B5455 G-1
4 Citation

Target: GPR30

Summary: GPR30 agonist, potent and selective

≥41.2 mg/mL
B5469 G-15
3 Citation

Target: GPR30

Summary: GPER receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥37 mg/mL
B3470 Etonogestrel

Target: Progesterone Receptors

Summary: steroidal progestin

insoluble in H2O; ≥15.05 mg/mL