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Signaling Pathways

Signaling Pathways

B2266 LDE225 (NVP-LDE225,Erismodegib)
1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
A8340 Cyclopamine
1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
B2307 LGK-974
1 Citation

Summary: PORCN inhibitor,potent and specific

insoluble in H2O; ≥19.8 mg/mL
A3543 LDE225 Diphosphate

Target: Smoothened

Summary: Smo antagonist

≥27.85 mg/mL
A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL