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Signaling Pathways

Signaling Pathways

A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL
A3785 Salinomycin

Target: Antibiotic

Summary: Polyether ionophore antibiotic;anti-cancer
B2266 LDE225 (NVP-LDE225,Erismodegib)
1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
A8182 3-Deazaneplanocin A (DZNep) hydrochloride
1 Citation

Target: EZH2

Summary: SAHH and EZH2 inhibitor

insoluble in EtOH; ≥14.94 mg/mL
B5833 GSK503
2 Citation

Summary: EZH2 inhibitor

≥21.65 mg/mL
B4678 CPI-169
1 Citation

Target: EZH2|EZH1

Summary: EZH2 inhibitor

≥26.45 mg/mL
B4687 iCRT 14

Summary: CRT inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.75 mg/mL
A8327 Verteporfin

Target: YAP

Summary: Photosensitizer used in photodynamic therapy

insoluble in EtOH; insoluble in H2O; ≥18.3 mg/mL
A8340 Cyclopamine
1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A8651 LY2940680

Target: Smoothened receptor

Summary: Hedgehog/SMO antagonist,inhibits Hh signaling