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Signaling Pathways

Signaling Pathways

A1615 GANT61
1 Citation

Target: GLI

Summary: GLI antagonist
A8327 Verteporfin

Target: YAP

Summary: Photosensitizer used in photodynamic therapy

insoluble in EtOH; insoluble in H2O; ≥18.3 mg/mL
A8340 Cyclopamine
1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A8500 PF-5274857

Summary: Smo antagonist,potent and selective

insoluble in EtOH; ≥17.6 mg/mL
A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL
A8396 CHIR-99021 (CT99021) HCl

Target: GSK-3

Summary: GSK-3α/β inhibitor

≥25.1 mg/mL
A8600 Tankyrase Inhibitors (TNKS) 22

Summary: Tankyrase inhibitor
A8601 Tankyrase Inhibitors (TNKS) 49

Target: Tankyrases

Summary: Tankyrase inhibitor

≥22.45 mg/mL
A8651 LY2940680

Target: Smoothened receptor

Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
A8652 JK 184

Summary: Hh signaling inhibitor

Soluble in DMSO