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Signaling Pathways

Signaling Pathways

A4481 PhiKan 083

Target: p53

Summary: p53 stabilizer

<13.74 mg/mL
A4483 PRIMA-1

Target: p53

Summary: BAX inhibitor

≥110.6 mg/mL
A4482 Pifithrin-μ
1 Citation

Target: Autophagy|p53|HSP70

Summary: Inhibitor of p53 binding and anti-apoptotic

insoluble in H2O; ≥18.1 mg/mL
A4208 NSC 319726

Target: p53

Summary: Reactivator of mutant p53
A4206 Pifithrin-α (PFTα)
2 Citation

Target: p53

Summary: p53 inhibitor

insoluble in H2O; ≥17.45 mg/mL
A4204 JNJ-26854165 (Serdemetan)
1 Citation

Target: p53|HDM2 ubiquitin ligase

Summary: P53 activator, blocking Mdm2-p53 interaction

insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
A4203 Tenovin-1

Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21

Summary: SIRT2 inhibitor, activates p53

insoluble in H2O; insoluble in EtOH; ≥15 mg/mL