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Signaling Pathways

Signaling Pathways

A4077 BIBR 953 (Dabigatran, Pradaxa)

Summary: Thrombin inhibitor,potent,reversible and direct

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A3126 5-R-Rivaroxaban

Target: Factor Xa

Summary: Factor Xa (FXa) inhibitor

≥20.85 mg/mL
A3381 Edoxaban

Target: Factor Xa

Summary: Factor Xa inhibitor

≥27.3 mg/mL
A3690 Otamixaban

Target: Factor Xa

Summary: Direct factor Xa inhibitors,potent and selective

≥22.35 mg/mL
A8363 Argatroban

Summary: Thrombin mediated fibrinogen cleavage inhibitor

≥25.25 mg/mL
A8381 BIBR-1048

Summary: Thrombin inhibitor

≥30 mg/mL