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Signaling Pathways

Signaling Pathways

B1115 BAY 87-2243

Target: Hypoxia Inducible Factors (HIFs)

Summary: HIF-1 inhibitor,potent and selective
A8660 Cilengitide
1 Citation

Target: Integrins

Summary: Integrin inhibitor for αvβ3 and αvβ5

≥29.43 mg/mL
A4509 PX 12

Target: Trx

Summary: Trx-1 inhibitor

insoluble in H2O; ≥8.75 mg/mL
A8233 DMXAA (Vadimezan)
2 Citation

Target: DT-diaphorases

Summary: Tumnor vascular disrupting agent, apoptosis inducer

insoluble in H2O; insoluble in EtOH; ≥14.1 mg/mL