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Signaling Pathways

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  1. ITD 1
    B5858 ITD 1
    Summary: The first selective TGFβ inhibitor
      ≥28.05 mg/mL
  2. Dasatinib Monohydrate
    B5954 Dasatinib Monohydrate
    Target: PDGFR|c-Kit|Bcr-Abl|Src
    Summary: Inhibitor of ABL, SRC, KIT, PDGFR, and other tyrosine kinases.
      ≥25.3 mg/mL
  3. Netarsudil (AR-13324)
    B7807 Netarsudil (AR-13324)
    Target: ROCK
    Summary: ROCK inhibitor
      ≥26.3 mg/mL
  4. Ro 31-8220
    B1287 Ro 31-8220
    Target: PKC
    Summary: pan-PKC inhibitor
      Soluble in DMSO
  5. Dequalinium Chloride
    B2191 Dequalinium Chloride
    Target: PKC|Calcium-Activated Potassium (KCa) Channels
    Summary: anti-tumor agent and PKC inhibitor
      insoluble in H2O; insoluble in ETOH; insoluble in DMSO
  6. LY364947
    B2287 LY364947
     1 Citation
    Summary: inhibitor of TGF-β type I receptor kinase domain
      insoluble in EtOH; insoluble in H2O; ≥24.4 mg/mL
  7. Pirfenidone
    B2288 Pirfenidone
    Summary: TGF-β production inhibitor
  8. GSK269962A
    B3392 GSK269962A
    Target: ROCK|RSK|MSK
    Summary: ROCK inhibitor
      Soluble in DMSO
  9. ZIP (SCRAMBLED)
    A8830 ZIP (SCRAMBLED)
    Summary: PKMζ inhibitor
      ≥192.8 mg/mL
  10. Midostaurin (PKC412)
    B3709 Midostaurin (PKC412)
    Target: PKC|PKA|KDR|Flk1|PPK|c-Syk|CDK1/CyclinB
    Summary: PKC inhibitor
      ≥57.1 mg/mL

Items 1-10 of 32

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