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Signaling Pathways

Signaling Pathways

A3008 Y-27632 dihydrochloride
19 Citation

Target: ROCK

Summary: ROCK1 inhibitor

≥111.2 mg/mL
A3478 Hydroxyfasudil

Target: ROCK|Rho-kinase

Summary: Rho-kinase inhibitor and vasodilator

Soluble in DMSO
B3523 Fasudil

Target: ROCK|PKC|PKG|PKA|Myosin light chain kinases (MLCKs)

Summary: calcium antagonist

Soluble in DMSO
A3771 RKI-1447

Target: ROCK

Summary: Potent ROCK1/ROCK2 inhibitor

insoluble in H2O; ≥16.3 mg/mL
A3825 SLx-2119
1 Citation

Target: ROCK

Summary: Selective ROCK2 inhibitor

≥22.65 mg/mL
A5506 Thiazovivin

Target: ROCK

Summary: ROCK inhibitor

≥15.55 mg/mL
A5611 GSK429286A

Target: ROCK

Summary: Selective ROCK1/ROCK2 inhibitor

≥21.6 mg/mL
A5734 Fasudil (HA-1077) HCl
1 Citation

Target: ROCK

Summary: Protein kinase inhibitor

≥16.4 mg/mL
B1293 Y-27632
9 Citation

Target: ROCK

Summary: ROCK inhibitor,potent and selective

≥24.7 mg/mL
B1294 SR-3677

Target: ROCK

Summary: Rho Kinase (ROCK-II) inhibitor

Soluble in DMSO