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Signaling Pathways

Signaling Pathways

A2213 17-DMAG (Alvespimycin) HCl
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

≥26.2 mg/mL
B7393 Gedunin

Target: HSP90

Summary: naturally occurring Hsp90 inhibitor

Soluble in DMSO
B4797 HSP990 (NVP-HSP990)

Target: HSP90

Summary: Hsp90 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥12.3 mg/mL
B4920 EC 144

Target: HSP90

Summary: High affinity, potent and selective Hsp90 inhibitor

<41.39 mg/mL
A4056 AT13387

Target: HSP90

Summary: Hsp90 inhibitor

insoluble in H2O; ≥13.25 mg/mL
A4057 AUY922 (NVP-AUY922)
1 Citation

Target: HSP90

Summary: Potent Hsp90 inhibitor

≥23.27 mg/mL
A4058 BIIB021

Target: HSP90

Summary: Hsp90 inhibitor,selective and competitive

insoluble in EtOH; insoluble in H2O; ≥14.95 mg/mL
A4060 Geldanamycin
2 Citation

Summary: Hsp90 inhibitor,potent and specific

insoluble in EtOH; insoluble in H2O; ≥16.9 mg/mL
A4061 IPI-504 (Retaspimycin hydrochloride)
3 Citation

Target: HSP90

Summary: Hsp90 inhibitor,novel, potent,selective

≥26.1 mg/mL
A4062 KW-2478

Target: HSP90

Summary: Potent Hsp90 inhibitor, novel, non-ansamycin,

≥100 mg/mL