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Signaling Pathways

Signaling Pathways

B7855 Alsterpaullone

Summary: CDKs and GSK3β inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.1 mg/mL
B1083 LEE011 hydrochloride

Summary: CDK inhibitor

Soluble in DMSO
B1084 LEE011 succinate

Summary: CDK inhibitor

Soluble in DMSO
B5220 [Ala92]-p16 (84-103)

Summary: inhibitor of cyclin-dependent kinase-4 (cdk4)/cyclin D1

Soluble to 2 mg/mL
B6935 Aminopurvalanol A

Target: Cyclin-Dependent Kinases

Summary: cyclin-dependent kinase inhibitor

Soluble in DMSO
B6956 NSC 625987

Summary: Cyclin-dependent kinase (cdk) 4 inhibitor

insoluble in ethanol; <27.13 mg/mL
A8882 THZ1
12 Citation

Target: Cyclin-Dependent Kinases

Summary: Covalent CDK7 inhibitor,potent and selective

≥28.3 mg/mL
B3707 ML167

Target: Clk

Summary: Clk4 inhibitor,highly selective

insoluble in EtOH; insoluble in H2O; ≥16.75 mg/mL
B4736 THZ1 Hydrochloride

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor

≥30.13 mg/mL
B6720 Kenpaullone

Summary: CDK1/cyclin B and GSK-3β inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.65 mg/mL