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APExBIO

LEE011 hydrochloride

In stock
Catalog No.
B1083
CDK inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$103.00
In stock
5mg
$94.00
In stock
10mg
$125.00
In stock
50mg
$234.00
In stock
100mg
$390.00
In stock

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Worldwide Distributors

LEE011 Hcl is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity.

Chemical Properties

StorageStore at -20°C
M.Wt471
Cas No.1211443-80-9
FormulaC23H31ClN8O
SolubilitySoluble in DMSO
Chemical Name(E)-7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)imino)-3,7-dihydro-2H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride
SDFDownload SDF
Canonical SMILESCN(C(C(N1C2CCCC2)=CC(C1=N/3)=CNC3=N/C4=NC=C(N5CCNCC5)C=C4)=O)C.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

LEE011 hydrochloride