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LEE011 hydrochloride CDK inhibitor

Catalog No.B1083
Size Price Stock Qty
5mg
$80.00
In stock
10mg
$120.00
In stock
25mg
$200.00
In stock
50mg
$250.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

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Chemical structure

LEE011 hydrochloride

LEE011 hydrochloride Dilution Calculator

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Chemical Properties

Cas No. 1211443-80-9 SDF Download SDF
Chemical Name (E)-7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)imino)-3,7-dihydro-2H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride
Canonical SMILES CN(C(C(N1C2CCCC2)=CC(C1=N/3)=CNC3=N/C4=NC=C(N5CCNCC5)C=C4)=O)C.Cl
Formula C23H31ClN8O M.Wt 471
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

LEE011 Hcl is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity.