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Signaling Pathways

Signaling Pathways

A4111 VX-680 (MK-0457,Tozasertib)

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A4112 Barasertib (AZD1152-HQPA)
3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4130 ENMD-2076

Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms

Summary: Selective Aurora A/Flt3 inhibitor

insoluble in H2O; ≥18.75 mg/mL
A4132 CCT137690

Target: Aurora Kinases

Summary: Aurora A/B/C inhibitor

insoluble in H2O; insoluble in EtOH; ≥6.89 mg/mL
A4114 MLN8054

Target: Aurora Kinases

Summary: Aurora A inhibitor

insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
A4115 JNJ-7706621
1 Citation

Target: Cyclin-Dependent Kinases|Aurora Kinases

Summary: Potent CDK/Aurora kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
A4116 Danusertib (PHA-739358)
2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL
A4121 SNS-314 Mesylate

Target: Aurora Kinases

Summary: Aurora A/B/C kinases inhibitor, potent and selective

≥26.35 mg/mL
A4122 PHA-680632

Target: Aurora Kinases|PLK|FGFR

Summary: Aurora kinase inhibitor,novel and potent

≥50.2 mg/mL
A4124 TAK-901

Target: Aurora Kinases|FLT3|Src|JAK|LRRK2|Hck|FGR|YES|Fyn|ARG

Summary: Novel Aurora A/B inhibitor

≥25.25 mg/mL