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Signaling Pathways

Signaling Pathways

A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL
A8807 MK-8745

Target: Aurora Kinases

Summary: Aurora A inhibitor,potent and selective

≥21.6 mg/mL
A4111 VX-680 (MK-0457,Tozasertib)

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A4112 Barasertib (AZD1152-HQPA)
3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4113 ZM 447439

Target: Aurora Kinases|MEK|Src|Lck

Summary: Aurora Kinase inhibitor,potent and selective

≥25.7 mg/mL
A4130 ENMD-2076

Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms

Summary: Selective Aurora A/Flt3 inhibitor

insoluble in H2O; ≥18.75 mg/mL
A4132 CCT137690

Target: Aurora Kinases

Summary: Aurora A/B/C inhibitor

insoluble in H2O; insoluble in EtOH; ≥6.89 mg/mL
A4114 MLN8054

Target: Aurora Kinases

Summary: Aurora A inhibitor

insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
A4115 JNJ-7706621
1 Citation

Target: Cyclin-Dependent Kinases|Aurora Kinases

Summary: Potent CDK/Aurora kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
A4116 Danusertib (PHA-739358)
2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL