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Signaling Pathways

Signaling Pathways

A8717 THZ2
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor

≥28.3 mg/mL
A3008 Y-27632 dihydrochloride
19 Citation

Target: ROCK

Summary: ROCK1 inhibitor

≥111.2 mg/mL
A4111 VX-680 (MK-0457,Tozasertib)

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A4113 ZM 447439

Target: Aurora Kinases|MEK|Src|Lck

Summary: Aurora Kinase inhibitor,potent and selective

≥25.7 mg/mL
A4114 MLN8054

Target: Aurora Kinases

Summary: Aurora A inhibitor

insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
A4115 JNJ-7706621
1 Citation

Target: Cyclin-Dependent Kinases|Aurora Kinases

Summary: Potent CDK/Aurora kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
A4127 GSK1070916

Target: Aurora Kinases

Summary: Aurora B/C inhibitor

≥25.4 mg/mL
A3210 AZ20
1 Citation

Target: ATM/ATR

Summary: ATR inhibitor,potent and selective

≥20.65 mg/mL
A3214 AZD1152
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor,highly potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
A3266 BS-181

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor,highly selective

Soluble in DMSO