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Signaling Pathways

Signaling Pathways

A3420 FMK

Target: Ribosomal s6 kinases (RSK)

Summary: RSK inhibitor

insoluble in H2O; ≥17.1 mg/mL
A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL
A3724 PI-103 Hydrochloride

Target: PI3K|mTOR|DNA-PK

Summary: DNA-PK/PI 3-kinase/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL
A8764 Rapalink-1

Target: mTOR

Summary: third-generation mTOR inhibitor

≥178.4 mg/mL
B1047 GDC-0032

Target: PI3K

Summary: PI3Kα inhibitor

≥23.05 mg/mL
B2186 GSK2636771

Target: PI3K

Summary: PIK3 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.83 mg/mL
B2178 BAY 80-6946 (Copanlisib)
1 Citation

Target: PI3K

Summary: PI3K inhibitor

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B1321 OTSSP167

Target: MELK

Summary: MELK inhibitor

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B2228 PF-4708671
1 Citation

Target: p70 rsk

Summary: P70 S6K1 isoform inhibitor,cell-permeable

≥37.8 mg/mL