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Signaling Pathways

Signaling Pathways

A4452 Mitomycin C
3 Citation

Summary: Inhibits DNA synthesis,antibiotic and antitumor agent

insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
A1769 KU-0060648
1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8624 CGK733

Target: ATM/ATR

Summary: ATM/ATR inhibitor,potent and selective

≥27.8 mg/mL
B4794 Santacruzamate A (CAY10683)

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor, potent and selective
A8171 Entinostat (MS-275,SNDX-275)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1 and HDAC3 inhibitor

insoluble in H2O; ≥18.8 mg/mL
A8176 Apicidin
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
A4090 JNJ-26481585
3 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
A4071 Fluorouracil (Adrucil)
3 Citation

Target: Thymidylate Synthase

Summary: Antitumor agent;inhibitor of thymidylate synthase

insoluble in EtOH; ≥10.04 mg/mL
A4098 PCI-24781 (CRA-024781)

Target: Histone Deacetylases (HDACs)

Summary: Pan-HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.75 mg/mL