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Signaling Pathways

Items 31-40 of 95

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  1. TH-302
    A3872 TH-302
    Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
      ≥22.45 mg/mL
  2. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  3. NSC 3852
    A4496 NSC 3852
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
  4. Pyroxamide
    A4497 Pyroxamide
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      Soluble in DMSO
  5. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  6. Mitomycin C
    A4452 Mitomycin C
     3 Citation
    Summary: Inhibits DNA synthesis,antibiotic and antitumor agent
      insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
  7. Floxuridine
    A2402 Floxuridine
    Target: Synthases/Synthetases
    Summary: Antineoplastic antimetabolite
      ≥12.31 mg/mL
  8. Carboplatin
    A2171 Carboplatin
    Summary: Antitumor agent that forms platinum-DNA adducts.
      insoluble in ETOH; ≥9.28 mg/mL
  9. Doxorubicin (Adriamycin) HCl
    A1832 Doxorubicin (Adriamycin) HCl
     2 Citation
    Target: Topoisomerases
    Summary: Antitumour antibiotic,inhibits TOPO II.
      ≥29 mg/mL
  10. Camptothecin
    A2877 Camptothecin
     1 Citation
    Target: Topoisomerases
    Summary: Topoisomerase I inhibitor,prototypic
      insoluble in H2O; insoluble in EtOH; ≥8.7 mg/mL

Items 31-40 of 95

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Category
  1. MTH11 item
  2. PARP8item
  3. ATM/ATR4item
  4. DNA Alkylating3item
  5. DNA Methyltransferase1 item
  6. DNA-PK4item
  7. DNA Synthesis27item
  8. HDAC31item
  9. Nucleoside Antimetabolite/Analogue2item
  10. Telomerase1 item
  11. Topoisomerase14item
Specificity
  1. Selective63item
Reversibility
  1. Reversible3item
Target
  1. Histone Deacetylases (HDACs)30item
  2. PI3K4item
  3. MDM21 item
  4. Thymidylate Synthase2item
  5. STAT1 item
  6. Estrogen and Related Receptors1 item
  7. EGFR1 item
  8. Tankyrases1 item
  9. DNA-PK3item
  10. TNKS1 item
  11. Topoisomerases11item
  12. ErbB1 item
  13. DNA Methyltransferases1 item
  14. PARP6item
  15. ATM/ATR4item
  16. HSV1 item
  17. Synthases/Synthetases1 item
  18. RNA Polymerases1 item
  19. FoxM11 item
  20. O6-methylguanine-DNA-methyl-transferase (MGMT)1 item
  21. Adenine receptors1 item
  22. RNA synthesis1 item
  23. FPTase1 item
  24. p531 item
  25. HDAC1 item
  26. PPAR1 item
  27. HCV polymerase1 item
  28. Antibiotic1 item
  29. DNA Alkylating2item
  30. Telomerases1 item
  31. Ribonucleotide Reductases1 item
  32. PTK1 item
  33. Adenosine Deaminases1 item
  34. DNA gyrase1 item
  35. 5-HT1 item
  36. ATM1 item
  37. MTH11 item
Related Disease
  1. Acute Myelogenous Leukemia2item
  2. Acute Myeloid Leukemia2item
  3. Bladder Cancer4item
  4. Breast Cancer17item
  5. Cancer64item
  6. Chronic Lymphocytic Leukemia1 item
  7. Colon Cancer8item
  8. Colon Carcinoma1 item
  9. Colorectal Cancer7item
  10. Dyskinesia1 item
  11. Epilepsy1 item
  12. Friedreich's Ataxia1 item
  13. Glioblastoma2item
  14. Glioma2item
  15. HCV1 item
  16. Hepatic Cancer1 item
  17. Hepatocellular Carcinoma3item
  18. HIV Infections1 item
  19. Inflammatory Diseases1 item
  20. Leukemia7item
  21. Liver Cancer1 item
  22. Lung Cancer6item
  23. Lymphoma6item
  24. Melanoma5item
  25. Multiple Myeloma3item
  26. Myeloma2item
  27. Neuroblastoma2item
  28. Neuronal Protection1 item
  29. Non-small Cell Lung Cancer3item
  30. Ovarian Cancer7item
  31. Pancreatic Cancer3item
  32. Prostate Cancer10item
  33. Renal Cancer1 item
  34. Renal Cell Carcinoma2item
  35. Testicular Cancer1 item