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Signaling Pathways

Items 11-20 of 234

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  1. BYK 49187
    A4526 BYK 49187
    Summary: Potent PARP-1/PARP-2 inhibitor
      <16.77 mg/mL
  2. DR 2313
    A4527 DR 2313
    Summary: PARP inhibitor
      ≥83.33 mg/mL
  3. EB 47
    A4528 EB 47
    Summary: Potent PARP-1 inhibitor
      <30.52 mg/mL
  4. JW 55
    A4529 JW 55
    Summary: PARP domain inhibitor
      insoluble in H2O; ≥19.25 mg/mL
  5. NU 1025
    A4530 NU 1025
    Summary: PARP inhibitor,potent and novel
      ≥41.67 mg/mL
  6. WIKI4
    A4531 WIKI4
    Summary: Inhibitor of Wnt/ß-Catenin signaling and tankyrase
      ≥26.1 mg/mL
  7. Mithramycin A
    A4546 Mithramycin A
    Summary: Anticancer antibiotic
      Soluble in DMSO
  8. LMK 235
    A4494 LMK 235
    Summary: HDAC4/HDAC5 inhibitor
  9. SBHA
    A4498 SBHA
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1/HDAC3 inhibitor,cell-permeable
      insoluble in EtOH; ≥9 mg/mL
  10. Mitomycin C
    A4452 Mitomycin C
     3 Citation
    Summary: Inhibits DNA synthesis,antibiotic and antitumor agent
      insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL

Items 11-20 of 234

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Category
  1. MTH14item
  2. PARP32item
  3. ATM/ATR10item
  4. DNA Alkylating9item
  5. DNA Ligases3item
  6. DNA Methyltransferase2item
  7. DNA-PK8item
  8. DNA Synthesis52item
  9. HDAC55item
  10. Nucleoside Antimetabolite/Analogue13item
  11. Telomerase5item
  12. Topoisomerase38item
  13. tankyrase5item
Specificity
  1. Selective72item
Reversibility
  1. Reversible4item
Target
  1. Histone Deacetylases (HDACs)34item
  2. PI3K5item
  3. MDM21 item
  4. mTOR1 item
  5. Thymidylate Synthase2item
  6. STAT1 item
  7. Estrogen and Related Receptors1 item
  8. EGFR1 item
  9. Tankyrases1 item
  10. DNA-PK4item
  11. TNKS1 item
  12. Topoisomerases11item
  13. ErbB1 item
  14. DNA Methyltransferases1 item
  15. PARP7item
  16. ATM/ATR6item
  17. AP endonucleases1 item
  18. HSV2item
  19. Synthases/Synthetases1 item
  20. RNA Polymerases1 item
  21. FoxM11 item
  22. O6-methylguanine-DNA-methyl-transferase (MGMT)1 item
  23. Adenine receptors1 item
  24. RNA synthesis1 item
  25. FPTase1 item
  26. p531 item
  27. HDAC1 item
  28. KDM1 item
  29. PPAR1 item
  30. HCV polymerase1 item
  31. Antibiotic1 item
  32. DNA Alkylating2item
  33. telomerase1 item
  34. Telomerases1 item
  35. Ribonucleotide Reductases1 item
  36. PTK1 item
  37. Adenosine Deaminases1 item
  38. DNA gyrase1 item
  39. DNA Ligases1 item
  40. 5-HT1 item
  41. PHF1 item
  42. ATM2item
  43. MTH11 item
Reported Experiments
  1. Animal Experiments95item
  2. Cell Experiments79item
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  2. Acute Myeloid Leukemia2item
  3. Bladder Cancer4item
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  5. Cancer68item
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  7. Colon Cancer10item
  8. Colon Carcinoma1 item
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  12. Friedreich's Ataxia1 item
  13. Glioblastoma2item
  14. Glioma2item
  15. HCV1 item
  16. Hepatic Cancer1 item
  17. Hepatocellular Carcinoma3item
  18. HIV Infections1 item
  19. Inflammatory Diseases1 item
  20. Leukemia7item
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  22. Lung Cancer6item
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  24. Melanoma5item
  25. Multiple Myeloma3item
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  28. Neuronal Protection1 item
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  30. Ovarian Cancer8item
  31. Pancreatic Cancer4item
  32. Prostate Cancer10item
  33. Renal Cancer1 item
  34. Renal Cell Carcinoma2item
  35. Testicular Cancer1 item