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Signaling Pathways

Signaling Pathways

A3843 SU 5402

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR2/FGFR/PDGFR/EGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
A3846 SU14813 maleate

Summary: VEGFR/PDGFR/Kit/FLT-3 inhibitor

Soluble in DMSO
A3847 SU5416

Target: VEGFR

Summary: VEGF receptor inhibitor and AHR agonist

insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
A3870 TG 100801

Target: VEGFR|FGFR|Src|Fyn kinase

Summary: Multi-kinase inhibitor

Soluble in DMSO
A3906 Vandetanib hydrochloride

Summary: VEGFR/EGFR inhibitor

≥51.2 mg/mL