JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home
Signaling Pathways

Signaling Pathways

A2822 AC480 (BMS-599626)

Target: EGFR

Summary: HER1/2 inhibitor,selective and efficacious

≥28.35 mg/mL
A1845 Canertinib (CI-1033)

Summary: HER family tyrosine kinase inhibitor
A5455 AEE788 (NVP-AEE788)

Summary: EGFR/HER-2/VEGFR inhibitor

≥22.05 mg/mL
A2024 PD168393

Target: PDGFR|FGFR|EGFR|PKC|insulin

Summary: EGFR inhibitor
A1173 AG-18

Summary: EGFR/PDGFR inhibitor
A2689 Butein

Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase

Summary: Protein kinase inhibitor

insoluble in H2O; ≥13.6 mg/mL
A1367 ALK-IN-1

Summary: Anaplastic lymphoma kinase (ALK) inhibitor

≥26.45 mg/mL
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8322 Neratinib (HKI-272)
1 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL
A8357 AG-1478

Target: EGFR

Summary: EGFR inhibitor,potent and selective

insoluble in H2O; ≥15.8 mg/mL