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Signaling Pathways

Signaling Pathways

A8218 Lapatinib
2 Citation

Target: ErbB

Summary: EGFR/HER2 inhibitor,potent,selective and reversible

≥29.05 mg/mL
A8215 PP 1

Target: Src|EGFR|JAK|ZAP-70

Summary: Src family tyrosine kinase inhibitor
A8320 PF-00562271

Target: FAK|Pyk2

Summary: FAK/Pyk2 inhibitor,potent and ATP-competitive

insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL
A8345 PF-562271 HCl

Target: FAK|Pyk2

Summary: FAK/Pyk2 inhibitor

≥26.35 mg/mL
A8440 GSK1838705A

Target: Insulin and Insulin-like Receptors|ALK

Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive

≥26.65 mg/mL
C3342 MAZ51

Target: VEGFR

Summary: VEGFR3 antagonist

insoluble in EtOH; insoluble in H2O; ≥31.4 mg/mL