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Signaling Pathways

Items 11-20 of 118

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  1. Sunitinib malate
    A8255 Sunitinib malate
     2 Citation
    Target: VEGFR
    Summary: VEGFR/PDGFRβ/ KIT/ FLT3/RET/CSF-1R inhibitor
      ≥26.65 mg/mL
  2. PHA-665752
    A2307 PHA-665752
     1 Citation
    Target: c-MET
    Summary: C-Met inhibitor,potent and ATP-competitive
  3. Ki8751
    A1821 Ki8751
    Target: VEGFR
    Summary: VEGFR-2 inhibitor,potent and selective
      ≥23.45 mg/mL
  4. SU11274
    A2678 SU11274
     2 Citation
    Target: MET
    Summary: C-Met inhibitor,potent and selective
      ≥28.4 mg/mL
  5. Masitinib (AB1010)
    A2942 Masitinib (AB1010)
    Target: PDGFR|c-Kit|Lyn
    Summary: Tyrosine kinase inhibitor, potent and selective
      ≥24.95 mg/mL
  6. PF-04217903
    A5096 PF-04217903
    Target: c-MET
    Summary: C-Met inhibitor,selective and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL
  7. SGX-523
    A1196 SGX-523
     1 Citation
    Target: MET
    Summary: MET inibitor, highly selective, ATP-competitive
      ≥17.95 mg/mL
  8. BMS-754807
    A1185 BMS-754807
    Target: Insulin and Insulin-like Receptors
    Summary: IGF-1R/InsR inhibitor,potent and selective
      ≥23.05 mg/mL
  9. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  10. Cediranib (AZD217)
    A1882 Cediranib (AZD217)
    Target: VEGFR
    Summary: VEGFR inhibitor receptor,highly potent
      ≥22.52 mg/mL

Items 11-20 of 118

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  1. Bcr-Abl5item
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Target
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  38. Myosin light chain kinases (MLCKs)1 item
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