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Signaling Pathways

Signaling Pathways

A4413 PD 150606

Target: Calpains

Summary: Non-peptide calpain inhibitor

Soluble in DMSO
A2213 17-DMAG (Alvespimycin) HCl
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

≥26.2 mg/mL
A8177 PAC-1
1 Citation

Target: Caspases

Summary: Procaspase-3 activator

insoluble in H2O; ≥13.4 mg/mL
B3941 Talabostat mesylate
2 Citation

Target: DPP-4

Summary: orally active, specific inhibitor of DPP4

≥11.45 mg/mL
A4064 NVP-BEP800

Target: HSP90

Summary: Oral Hsp90β inhibitor, novel, fully synthetic
A4386 Elesclomol (STA-4783)
3 Citation

Summary: Oxidative stress/apoptosis inducer,potent and novel

insoluble in H2O; ≥20.15 mg/mL
A4388 XL-888
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL