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Signaling Pathways

Items 91-100 of 241

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  1. BAY-678
    C4325 BAY-678
    Summary: HNE inhibitor
      ≤30 mg/mL
  2. UCF 101
    C4437 UCF 101
    Summary: inhibitor of the proteolytic activity of Omi/HtrA2
      ≤5 mg/mL
  3. cis-ACCP
    C4501 cis-ACCP
    Summary: type IV collagen-specific MMP-2 and MMP-9 inhibitor
      ≤0.15 mg/mL
  4. Equisetin
    C4787 Equisetin
    Summary: HIV-1 integrase inhibitor
      Soluble in DMSO;Soluble in dimethyl formamide
  5. 2-cyano-Pyrimidine
    C5038 2-cyano-Pyrimidine
    Summary: cathepsin K inhibitor
      insoluble in EtOH; ≥24.2 mg/mL
  6. o-Phenanthroline
    B7854 o-Phenanthroline
    Summary: metalloprotease inhibitor
      insoluble in H2O; ≥360.42 mg/mL
  7. Calpain Inhibitor XII
    C5347 Calpain Inhibitor XII
    Summary: reversible and selective inhibitor of calpain I
      ≤16 mg/mL
  8. Tosyllysine Chloromethyl Ketone (hydrochloride)
    C5839 Tosyllysine Chloromethyl Ketone (hydrochloride)
    Summary: serine proteinases inhibitor
      insoluble in EtOH; ≥16.3 mg/mL
  9. Chymostatin
    C5589 Chymostatin
    Summary: chymotryptase-like serine proteases inhibitor
      ≤10 mg/mL
  10. MMP-2/MMP-9 Inhibitor I
    C5598 MMP-2/MMP-9 Inhibitor I
    Summary: potent inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9
      ≤25mM in DMSO

Items 91-100 of 241

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  1. Caspase25item
  2. Aminopeptidase8item
  3. ACE9item
  4. Calpains11item
  5. Carboxypeptidase4item
  6. Cathepsin12item
  7. DPP-418item
  8. Elastase10item
  9. Gamma Secretase18item
  10. HCV Protease15item
  11. HSP25item
  12. HIV Integrase12item
  13. HIV Protease13item
  14. MMP25item
  15. NS3/4a protease4item
  16. Serine Protease9item
  17. Thrombin14item
  18. Urokinase2item
  19. Other Proteases11item
  20. Tyrosinases1 item
Specificity
  1. Selective80item
  2. Non-Selective1 item
Reversibility
  1. Reversible14item
  2. Irreversible13item
Target
  1. Caspases13item
  2. Proteasome1 item
  3. Cathepsins11item
  4. MMP6item
  5. Factor Xa3item
  6. Thymidylate Synthase1 item
  7. Aminopeptidases3item
  8. HSP9012item
  9. Notch1 item
  10. thrombin1 item
  11. Renin1 item
  12. HIV proteases1 item
  13. Pepsins1 item
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  17. Trypsins1 item
  18. Trypsin1 item
  19. Chymotrypsin1 item
  20. Kallikrein1 item
  21. Trypsinogen1 item
  22. HIV-1 gp1201 item
  23. HIV Integrases2item
  24. Urokinases1 item
  25. Inward Rectifier Potassium (Kir) Channels1 item
  26. Papains1 item
  27. DPP-45item
  28. Nonstructural protein 5B (NS5B)1 item
  29. ADAMs1 item
  30. Dipeptidyl-peptidase II1 item
  31. metalloprotease1 item
  32. cysteine protease2item
  33. HCV polymerase2item
  34. Subtilisin/Kex2p-like proprotein convertase1 item
  35. Elastases1 item
  36. integrase1 item
  37. HCV NS3-4A protease1 item
  38. NE1 item
Reported Experiments
  1. Animal Experiments90item
  2. Cell Experiments69item
Related Disease
  1. Acute Lung Injury1 item
  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer11item
  4. Cancer35item
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  6. Clear Cell Renal Cell Carcinoma1 item
  7. Colon Cancer2item
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  10. HCV3item
  11. Hepatitis C4item
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  14. Inflammatory Diseases1 item
  15. Lung Cancer3item
  16. Lymphoma1 item
  17. Melanoma7item
  18. Multiple Myeloma2item
  19. Neuroblastoma1 item
  20. Non-small Cell Lung Cancer2item
  21. Osteoporosis1 item
  22. Ovarian Cancer4item
  23. Pancreatic Cancer3item
  24. Prostate Cancer3item
  25. Psoriasis1 item
  26. Renal Cell Carcinoma1 item
  27. Rheumatoid Arthritis3item
  28. Squamous Cell Carcinoma1 item
  29. Type 2 Diabetes1 item