Search results for: 'research area tyrosine kinase insulin receptor'
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BA8818 TolebrutinibSummary: Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier-crossing inhibitor of Bruton's tyrosine kinase with values of 0.4 and 0.7 nM in RamosB cells and HMC microglia, respectively. -
B5954 Dasatinib MonohydrateTarget: PDGFR|c-Kit|Bcr-Abl|SrcSummary: Inhibitor of ABL, SRC, KIT, PDGFR, and other tyrosine kinases. - BA8118 PTP1B-IN-15Summary: PTP1B-IN-15 is a potent and selective protein tyrosine phosphatase 1B inhibitor.
- BA9011 eCF506Summary: eCF506 is a potent, orally active inhibitor of non-receptor tyrosine kinases.
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B3709 Midostaurin (PKC412)Target: PKC|PKA|KDR|Flk1|PPK|c-Syk|CDK1/CyclinBSummary: PKC inhibitor -
A4193 SMI-4aTarget: PimSummary: Potent Pim inhibitor - BA9033 UNC1062Summary: UNC1062 is a selective tyrosine kinase inhibitor that reduces MERTK-mediated activation of downstream signaling, induces apoptosis in culture, reduces colony formation in soft agar, and inhibits melanoma cell invasion.
- C8171 DigitoxoseSummary: Digitoxose (D-(+)-Digitoxose), a natural product that specifically and competitively inhibits glucose-stimulated insulin release from pancreatic islets in lean and obese mice.
- BA3507 RIPK1-IN-4Summary: RIPK1-IN-4 is a potent inhibitor of type II kinase receptor-interacting protein 1 kinase.
- BA5146 HigenamineSummary: Higenamine (Norcoclaurine) is an agonist, a key component of the Chinese herb aconite, which is used in heart failure research.