Tolebrutinib
Catalog No.
BA8818
Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier-crossing inhibitor of Bruton's tyrosine kinase with values of 0.4 and 0.7 nM in RamosB cells and HMC microglia, respectively.
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Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier-crossing inhibitor of Bruton's tyrosine kinase, with values of 0.4 and 0.7 nM in RamosB cells and HMC microglia, respectively.Tolebrutinib is efficacious in CNS immunization. Tolebrutinib may be used in multiple sclerosis (MS) studies.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 455.51 |
Cas No. | 1971920-73-6 |
Formula | C26H25N5O3 |
Synonyms | SAR442168;PRN2246 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |