Search results for: 'research area apoptosis bcl xl'
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BA3122 CrolibulinSummary: Crolibulin (EPC2407) is a microtubule protein polymerization inhibitor that induces apoptosis and inhibits cell growth. - BA3146 LDCASummary: LDCA is a double-hit metabolic regulator that inhibits enzyme activity and stimulates apoptosis in malignant populations.
- BA3240 DPBQSummary: DPBQ activates and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerases or bind DNA.
- BA2783 BTdCPUSummary: BTdCPU is a heme-regulated inhibitory kinase activator that promotes phosphorylation and induces apoptosis in (Dex)-resistant cancer cells.
- BA3210 8-HydroxyefavirenzSummary: 8-Hydroxyefavirenz is the major metabolite and 8-Hydroxyefavirenz induces apoptosis in primary human hepatocytes through and BimEL-dependent mechanism.
- BA3292 LQZ-7FSummary: LQZ-7F is a survivin dimerization inhibitor that induces spontaneous apoptosis and synergizes with doxorubicin in prostate cancer cells.
- BA3300 PeruvosideSummary: Peruvoside induces apoptosis and autophagy and has broad-spectrum antitumor activity in breast, lung, liver and leukemia.
- BA3303 DD1Summary: DD1 is a proteasome inhibitor activated during apoptosis in acute myeloid leukemia (AML) that degrades P70S6K.
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BA2747 MRT-2359Summary: MRT-2359 is a potent, orally active and selective degrader (>30nM and <300nM) that specifically induces protein translation-dependent apoptosis. - BA2990 TL4-12Summary: TL4-12 is a selective inhibitor that downregulates IKZF1 and BCL-6 and inhibits MM cell proliferation (IC=37nM) and induces apoptosis.