MRT-2359
Catalog No.
BA2747
MRT-2359 is a potent, orally active and selective degrader (>30nM and <300nM) that specifically induces protein translation-dependent apoptosis.
Featured Products
MRT-2359 is a potent, orally active and selective degradative agent (>30nM and <300nM) that specifically induces protein translation-dependent apoptosis.MRT-2359 exhibits significant and preferential antiproliferative activity in a wide range of cancer cell lines, particularly in MYC-driven cell lines such as non-small cell with high expression of N-Myc or L-Myc lung cancer (NSCLC) and small cell lung cancer (SCLC).MRT-2359 inhibits the growth of drug-resistant NSCLC and SCLC cells and can be used for tumor research.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 495.38 |
| Cas No. | 2803881-11-8 |
| Formula | C22H17F4N3O6 |
| Chemical Name | (2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-5-yl)methyl (2-fluoro-5-(trifluoromethoxy)phenyl)carbamate |
| SDF | Download SDF |
| Canonical SMILES | FC1=CC=C(OC(F)(F)F)C=C1NC(OCC2=CC=C3C(C(N(C4C(NC(CC4)=O)=O)C3)=O)=C2)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
