Search results for: 'pi3 kinase p110'
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BA8912 Dyrk1A-IN-3Summary: Dyrk1A-IN-3 is a highly selective bispecific tyrosine-regulated kinase 1A inhibitor that binds DYRK1A with high affinity (=76nM). - BA9000 GSK3179106Summary: GSK3179106 is an orally active, selective kinase inhibitor with 0.4 nM and 0.2 nM for human and rat, respectively.
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A3133 A 83-01Summary: ALK-5 inhibitor - BA1646 K6PC-5Summary: K6PC-5, a ceramide derivative, is a sphingosine kinase 1 activator that causes a transient and rapid increase in intracellular calcium levels.
- BA7183 BKIDC-1553Summary: BKIDC-1553 is an orally effective antiglycolytic agent and collision kinase inhibitor derivative with a predicted half-life of approximately 17h in humans.
- BA8865 AZD3229Summary: AZD3229 is a potent and broadly available mutant tyrosine kinase receptor inhibitor for developmental studies of gastrointestinal mesenchymal tumors.
- BA8948 IrpagratinibSummary: Irpagratinib (ABSK011) is an orally active inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase, targeted (IC50<10nM).
- BA8989 ZeteletinibSummary: Zeteletinib (BOS-172738; DS-5010) is an orally effective, selective kinase inhibitor with nanomolar potency against and >300-fold selectivity for VEGFR2.
- BA9120 GA-017Summary: GA-017 is a potent selective and (large tumor suppressor kinase 1/2) inhibitor with values of 4.10 and 3.92 nM, respectively.
- BA4214 KIRA-7Summary: KIRA-7 is an imidazopyrazine compound that binds to the kinase (for 110 nM) to inhibit its RNase activity in a metastable manner.