Irpagratinib
Catalog No.
BA8948
Irpagratinib (ABSK011) is an orally active inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase, targeted (IC50<10nM).
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Irpagratinib (ABSK011) is an orally active inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase, targeted (IC50<10nM).Irpagratinib inhibits autophosphorylation and blocks signaling from to downstream pathway activation.Irpagratinib has shown antitumor activity in PK studies in mice, rats and dogs showed high exposure and antitumor activity in subcutaneous xenograft tumor models.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 570.59 |
| Cas No. | 2230974-62-4 |
| Formula | C28H32F2N6O5 |
| Synonyms | ABSK011 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |