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Recombinant Human IGF1, Tag Free

Catalog No.
PH1004
 
Grouped product items
SizePriceStock Qty
10ug
$15.00
Ship with 5-10 days
50ug
$27.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue. IGF-1 binds and interacts with the IGF-1 binding proteins (IGFBPs). IGF-1 binds to the IGF-1 receptor with a higher affinity than the insulin receptor.

Human IGF-I is synthesized as two precursor isoforms with N- and alternate C-terminal propeptides, which are proteolyzed to produce the identical 7.6 kDa mature IGF-I. Mature human IGF I shares 94% and 96% aa sequence identity with mouse IGF1 and rat IGF1, respectively, and exhibits cross species activity. Human IGF-1 is a 7.6 kDa protein containing 70 amino acid residues. The recombinant human IGF-1 was produced using animal origin free technology.

Reference:
1. Zhao Y, Wang Q, et al. "Glutamine protects against oxidative stress injury through inhibiting the activation of PI3K/Akt signaling pathway in parkinsonian cell model." Environ Health Prev Med. 2019 Jan 5;24(1):4.

Description

Synonym IGF1A, Insulin-Like Growth Factor 1, Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Gene ID 3479
Accession # P05019
Molecular Characterization Gly49-Ala118
M.Wt 7.6 kDa
Source 293T cells
Bio Activity Determined by the dose-dependent stimulation of murine CTLL-2 cells:
ED50:< 0.1 ng/mL
Specific activity: > 1x107units/mg.

Quality Control

Quality Control & MSDS

View current batch:
    Purity ≥ 95%, by SDS-PAGE and HPLC.
    Endotoxin Level: < 0.1 ng/μg
  • Datasheet
 

Components and Storage

Formulation The protein is dissolved in PBS buffer.
Storage

This product is stable after storage at:

4°C for 1 week;

-20°C for 3 months.

Please avoid repeated freeze-thaw cycles.